Description

1-(4'-Trifluoromethyl-Biphenyl-4-Yl)-Ethanone is a high-purity, specialized organic intermediate featuring a biphenyl core substituted with a trifluoromethyl group and an acetyl moiety. This compound matters for its role as a critical building block in advanced synthesis, offering unique electronic and steric properties imparted by the fluorine atoms. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients, as well as by manufacturers of advanced materials such as liquid crystals and organic semiconductors.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or dopant in the production of organic light-emitting diodes (OLEDs), liquid crystal displays (LCDs), and other electronic materials.
• Chemical Research & Development: Employed as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorinated Compound Production: Acts as a starting material for synthesizing more complex fluorinated aromatic compounds used in various high-value chemical applications.

Basic Information

Product Name	1-(4'-Trifluoromethyl-Biphenyl-4-Yl)-Ethanone
CAS No.	142557-76-4
Molecular Formula	C15H11F3O
Molecular Weight	264.24 g/mol
Synonyms	4'-Trifluoromethyl-4-acetylbiphenyl; 1-[4'-(Trifluoromethyl)[1,1'-biphenyl]-4-yl]ethanone; 4-Acetyl-4'-trifluoromethylbiphenyl; p-Acetyl-p'-(trifluoromethyl)biphenyl; 4-(Trifluoromethyl)-[1,1'-biphenyl]-4'-yl methyl ketone; Ethanone, 1-[1,1'-biphenyl]-4-yl-4'-(trifluoromethyl)-; [1,1'-Biphenyl]-4-acetophenone, 4'-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 1-(4'-Trifluoromethyl-Biphenyl-4-Yl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are available upon request, providing full traceability and quality assurance for your projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.