Description

(+)-1,2-Bis((2S,5S)-2,5-Diethylphospholano)Benzene(Cyclooctadiene)Rhodium (I) Trifluoromethanesulfonate is a high-purity, chiral transition metal complex designed for advanced asymmetric synthesis. This compound serves as a highly efficient and selective catalyst, enabling the production of enantiomerically pure intermediates critical for pharmaceutical and fine chemical manufacturing. It is an essential tool for R&D scientists and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to optimize stereoselective hydrogenation and related catalytic transformations.

Application

• Asymmetric Hydrogenation Catalyst: A premier catalyst for the enantioselective reduction of prochiral olefins, enamides, and ketones to produce chiral building blocks.
• Pharmaceutical Intermediate Synthesis: Critical in the synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric excess (ee), such as chiral amines and amino acid derivatives.
• Agrochemical Manufacturing: Used in the production of chiral herbicides, fungicides, and pesticides where biological activity is stereospecific.
• Fine Chemical Production: Enables the manufacture of high-value chiral flavors, fragrances, and electronic chemicals.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new catalytic pathways in asymmetric synthesis.
• Process Chemistry Optimization: Employed for scaling up stereoselective reactions from laboratory to pilot plant and commercial production.

Basic Information

Product Name	(+)-1,2-Bis((2S,5S)-2,5-Diethylphospholano)Benzene(Cyclooctadiene)Rhodium (I) Trifluoromethanesulfonate
CAS No.	142184-30-3
Molecular Formula	C30H48F3O3P2RhS
Molecular Weight	722.66 g/mol
Synonyms	(+)-[Rh((S,S)-Et-DuPHOS)(COD)]OTf; (S,S)-Et-DuPHOS Rh(COD) Triflate; Rhodium(I)-(S,S)-1,2-Bis(2,5-diethylphospholano)benzene(1,5-cyclooctadiene) trifluoromethanesulfonate; (S,S)-Et-DuPHOS-Rh(COD)OTf; DuPHOS Rhodium Catalyst; Rh-(S,S)-Et-DuPHOS(COD)OTf; Asymmetric Hydrogenation Catalyst (Rh-Et-DuPHOS); [Rh((S,S)-Et-DuPHOS)(nbd)]OTf (related complex)
EINECS	Contact for details

Quality Control

Every batch of our chiral rhodium catalyst is produced and tested under strict quality control protocols to ensure exceptional purity and consistent catalytic performance. We provide comprehensive Certificates of Analysis (COA) detailing critical parameters such as Rhodium content, enantiomeric purity of the ligand, and solvent residues. Our manufacturing aligns with cGMP principles where applicable, supporting its use in regulated pharmaceutical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. This material is easily oxidized and moisture-sensitive; prolonged exposure to air or ambient conditions should be avoided to maintain catalytic activity.

Specification

Item	Specification
Appearance	Orange to red-brown solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Rhodium Content	Contact for details
Solvent Residues (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.