Description

2-(4-Bromobutyl)-1,3,2-benzodioxaborole is a specialized organoboron reagent featuring a reactive bromobutyl side chain. This compound is valued for its dual functionality, serving as a versatile building block in advanced synthetic chemistry, particularly in cross-coupling and polymer modification reactions. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, especially those incorporating boron-based functional groups.
• Suzuki-Miyaura Cross-Coupling: Acts as a stable, handleable boronic ester precursor for palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Polymer & Material Science: Used in the modification and functionalization of polymers, and in the development of organic electronic materials and OLEDs.
• Agrochemical Synthesis: Intermediate in the production of advanced crop protection agents and herbicides.
• Ligand & Catalyst Development: Serves as a precursor for creating novel bidentate ligands and organometallic catalysts.
• Chemical Biology Probes: Utilized in the design and synthesis of boron-containing probes for bioimaging and diagnostic applications.

Basic Information

Product Name	2-(4-Bromobutyl)-1,3,2-benzodioxaborole
CAS No.	142172-51-8
Molecular Formula	C11H14BBrO2
Molecular Weight	269.94 g/mol
Synonyms	4-Bromobutyl Benzodioxaborole; 1,3,2-Benzodioxaborole, 2-(4-bromobutyl)-; 2-(4-Bromobutyl)benzo[d][1,3,2]dioxaborole; (4-Bromobutyl)benzodioxaborole; 4-BBB; 2-(4-Bromobutyl)-1,3,2-benzodioxaborolane; Bromobutyl Benzodioxaborole
EINECS	Contact for details

Quality Control

Our production of 2-(4-Bromobutyl)-1,3,2-benzodioxaborole adheres to stringent in-process controls to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized by NMR (1H, 13C, 11B), HPLC, and GC analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Purity (NMR)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.