Description

(Rs)-2-[(1-Benzyl-4-Piperidyl)Methyl]-5,6-Dimethoxyindan-1-One is a high-purity chiral intermediate featuring a complex molecular architecture that combines indanone and piperidine motifs. This compound matters for its critical role as a sophisticated building block in the synthesis of advanced pharmaceutical agents, particularly those targeting the central nervous system. It is primarily needed by research institutions and pharmaceutical development companies engaged in creating novel therapeutic compounds, where precise stereochemistry and reliable quality are paramount for successful outcomes.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the research and development of potential drug candidates, especially for neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its complex, drug-like scaffold.
• Asymmetric Synthesis: Serves as a valuable substrate or intermediate in catalytic asymmetric reactions to create enantiomerically pure compounds.
• Reference Standard: Employed as an analytical standard in method development and quality control for pharmaceutical manufacturing.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and protein interactions.
• Process Chemistry Development: Acts as a critical intermediate for scaling up synthetic routes from laboratory to pilot plant scale.

Basic Information

Product Name	(Rs)-2-[(1-Benzyl-4-Piperidyl)Methyl]-5,6-Dimethoxyindan-1-One
CAS No.	142057-79-2
Molecular Formula	C25H31NO3
Molecular Weight	393.52 g/mol
Synonyms	2-[(1-Benzyl-4-piperidinyl)methyl]-5,6-dimethoxy-1-indanone; 5,6-Dimethoxy-2-[(1-benzyl-4-piperidinyl)methyl]-1-indanone; (RS)-2-((1-Benzylpiperidin-4-yl)methyl)-5,6-dimethoxy-2,3-dihydro-1H-inden-1-one; 142057-79-2; BZP-DMI; Benzylpiperidinylmethyldimethoxyindanone
EINECS	Contact for details

Quality Control

Our (Rs)-2-[(1-Benzyl-4-Piperidyl)Methyl]-5,6-Dimethoxyindan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (by chiral HPLC)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.