Description

4-Bromo-3-Bromomethyl-Benzoic Acid Methyl Ester is a high-purity, multi-functional brominated aromatic ester that serves as a critical synthetic intermediate. Its value lies in its versatile reactivity, offering two distinct bromine handles for selective functionalization, which is essential for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in medicinal chemistry and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the bromomethyl group enables further coupling reactions.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of specialty chemicals for electronic displays and organic light-emitting diodes due to its aromatic core and functional handles.
• Polymer Modification: Employed to introduce bromine functional groups into polymer chains, altering properties like flame retardancy or reactivity for further grafting.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions such as Suzuki, Heck, or Sonogashira couplings to create complex biaryl and conjugated systems.
• Chemical Research & Development: A versatile reagent in academic and industrial labs for exploring new synthetic pathways and creating custom chemical libraries.

Basic Information

Product Name	4-Bromo-3-Bromomethyl-Benzoic Acid Methyl Ester
CAS No.	142031-67-2
Molecular Formula	C10H10Br2O2
Molecular Weight	322.00 g/mol
Synonyms	Methyl 4-Bromo-3-(bromomethyl)benzoate; Benzoic acid, 4-bromo-3-(bromomethyl)-, methyl ester; 3-(Bromomethyl)-4-bromobenzoic acid methyl ester; Methyl 3-(bromomethyl)-4-bromobenzoate; 4-Bromo-3-bromomethyl methyl benzoate
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-3-Bromomethyl-Benzoic Acid Methyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your synthetic processes. Each lot is fully characterized and tested against comprehensive specifications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.