Description

(S)-Tetrahydro-2H-Pyran-3-Carbaldehyde is a chiral aldehyde building block of significant importance in modern synthetic organic chemistry. Its value lies in its stereodefined structure, which is crucial for the asymmetric synthesis of complex molecules. This high-purity intermediate is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where specific stereochemistry is essential for biological activity and environmental safety.
• Asymmetric Catalysis & Ligand Development: Serves as a precursor for chiral ligands and catalysts used in enantioselective transformations.
• Fine Chemical Production: Employed in the multi-step synthesis of complex natural products, flavors, and fragrances requiring high stereochemical purity.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and for creating compound libraries for screening.

Basic Information

Product Name	(S)-Tetrahydro-2H-Pyran-3-Carbaldehyde
CAS No.	141822-85-7
Molecular Formula	C6H10O2
Molecular Weight	114.14 g/mol
Synonyms	(S)-3-Formyltetrahydro-2H-pyran; (S)-Tetrahydro-2H-pyran-3-carboxaldehyde; (3S)-Oxane-3-carbaldehyde; (S)-3-Pyrancarboxaldehyde, tetrahydro-; (S)-THP-3-Carbaldehyde; (S)-3-Formyltetrahydropyran; (S)-3-Carboxaldehydetetrahydro-2H-pyran
EINECS	Contact for details

Quality Control

Our (S)-Tetrahydro-2H-Pyran-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage or after opening to maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.