Description

(2R)-(+)-3,3-Dimethylglycidyl is a high-purity, chiral epoxide building block of significant importance in asymmetric synthesis. Its value lies in its ability to introduce the (2R)-glycidyl moiety, a key structural feature for imparting specific stereochemistry in advanced pharmaceutical intermediates and fine chemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure precursors for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of β-blockers, antiviral agents, and other active pharmaceutical ingredients (APIs) requiring specific (R)-configuration.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators where stereochemistry affects biological activity.
• Fine Chemical Building Block: Serves as a versatile starting material for chiral ligands, catalysts, and complex organic molecules in research and development.
• Polymer Modification: Employed to introduce reactive epoxy groups into polymer chains for cross-linking or to create specialty polymers with tailored properties.
• Asymmetric Catalysis Research: A valuable substrate for developing and testing new asymmetric ring-opening reactions and other catalytic methodologies.

Basic Information

Product Name	(2R)-(+)-3,3-Dimethylglycidyl
CAS No.	141700-91-6
Molecular Formula	C5H8O2
Molecular Weight	100.12 g/mol
Synonyms	(R)-(+)-3,3-Dimethylglycidol; (2R)-(-)-3,3-Dimethyloxiranemethanol; (R)-(-)-3,3-Dimethylglycidol; (R)-(+)-3,3-Dimethylglycidyl alcohol; (2R)-3,3-Dimethyl-2-oxiranemethanol; (R)-3,3-Dimethylglycidol; (+)-3,3-Dimethylglycidol; (R)-Glycidol, 3,3-dimethyl-
EINECS	Contact for details

Quality Control

Our (2R)-(+)-3,3-Dimethylglycidyl is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, assay by GC or HPLC, and identity confirmation by IR and NMR spectroscopy. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use and stored away from heat and ignition sources.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.