Description

n-[(1S,2R)-2-Hydroxycyclohexyl]Acetamide CAS NO 141553-13-1 is a chiral, high-purity organic compound featuring a cyclohexyl ring with defined stereochemistry. This compound matters as a versatile chiral building block and intermediate, essential for the synthesis of complex molecules where stereochemical integrity is critical. It is primarily needed by pharmaceutical R&D teams, agrochemical manufacturers, and fine chemical producers developing active ingredients, catalysts, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Synthesis: Used in the production of advanced, stereospecific pesticides and herbicides where the specific isomer configuration enhances efficacy and reduces environmental impact.
• Catalyst & Ligand Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to create enantiomerically pure compounds.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require high stereochemical purity.
• Academic & Industrial Research: A valuable reference standard and starting material in organic chemistry research for studying stereoselective reactions and metabolic pathways.

Basic Information

Product Name	n-[(1S,2R)-2-Hydroxycyclohexyl]Acetamide
CAS No.	141553-13-1
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	(1S,2R)-2-Acetamidocyclohexanol; N-[(1S,2R)-2-Hydroxycyclohexyl]acetamide; (1S,2R)-N-(2-Hydroxycyclohexyl)acetamide; Acetamide, N-[(1S,2R)-2-hydroxycyclohexyl]-; trans-2-Acetamidocyclohexanol; (1S,2R)-2-(Acetylamino)cyclohexanol; Chiral Cyclohexyl Acetamide Derivative
EINECS	Contact for details

Quality Control

Our n-[(1S,2R)-2-Hydroxycyclohexyl]Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.