Description

Pyridine, 3-(3-Fluoro-3H-Diazirin-3-Yl)- (9Ci) is a specialized heterocyclic compound that serves as a critical photoaffinity labeling reagent and chemical probe in advanced research. Its core value lies in its unique diazirine and fluorine functionalities, enabling precise covalent cross-linking and tracking of biomolecular interactions under mild, controlled photolysis. This high-purity intermediate is essential for researchers and developers in pharmaceutical discovery, proteomics, and chemical biology, facilitating the study of protein-ligand binding, target identification, and metabolic pathways.

Application

• Photoaffinity Labeling (PAL): As a key reagent for covalent capture and identification of biological targets in drug discovery.
• Chemical Proteomics: For activity-based protein profiling (ABPP) and mapping enzyme active sites.
• Bioconjugation & Probe Synthesis: Used to synthesize fluorescent, biotinylated, or other tagged probes for imaging and detection.
• Metabolic Pathway Analysis: Employed to tag and trace small molecules within complex biological systems.
• Material Science Research: As a photo-crosslinker for surface functionalization and polymer modification studies.
• Academic & Industrial R&D: Fundamental research tool in medicinal chemistry and biochemistry laboratories.

Basic Information

Product Name	Pyridine, 3-(3-Fluoro-3H-Diazirin-3-Yl)- (9Ci)
CAS No.	141342-10-1
Molecular Formula	C7H5FN3
Molecular Weight	150.14 g/mol
Synonyms	3-(3-Fluoro-3H-diazirin-3-yl)pyridine; 3-Pyridinyldiaziridine, 3-fluoro-; 3-(3-Fluorodiazirin-3-yl)pyridine; 3-(3-Fluoro-3H-diazirin-3-yl)pyridine; Photoaffinity Labeling Reagent; Fluorinated Diazirine Pyridine; PAL Probe; Contact for details on EINECS.

Quality Control

Our production of Pyridine, 3-(3-Fluoro-3H-Diazirin-3-Yl)- (9Ci) adheres to stringent quality protocols suitable for research and development applications. Each batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific chromatographic and spectroscopic data are provided to support your critical work. We ensure traceability and compliance with relevant standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid or light-sensitive liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.