Description

Oxirane, (2-Methoxyphenyl)-, (-)- (9Ci) is a chiral epoxide derivative of 2-methoxyphenol, serving as a valuable synthetic intermediate in advanced organic chemistry. Its enantiomerically pure form is critical for achieving high stereoselectivity in the synthesis of complex molecules, ensuring the production of single-isomer products with defined biological activity. This compound is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of enantiomerically pure drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry is required for optimal efficacy and environmental safety.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and catalysts used in asymmetric synthesis, enhancing reaction selectivity and yield.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require precise stereochemical control.
• Academic and R&D: Utilized in university and industrial research laboratories for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	Oxirane, (2-Methoxyphenyl)-, (-)- (9Ci)
CAS No.	141303-38-0
Molecular Formula	C9H10O2
Molecular Weight	150.17 g/mol
Synonyms	(-)-2-Methoxyphenyloxirane; (2R)-2-(2-Methoxyphenyl)oxirane; (-)-2-(2-Methoxyphenyl)oxirane; (R)-(-)-2-(2-Methoxyphenyl)oxirane; Guaiacol glycidyl ether, (-)-; 1,2-Epoxy-3-(2-methoxyphenyl)propane, (-)-; (R)-Guaiacol glycidyl ether; (R)-2-(2-Methoxyphenoxy)methyl)oxirane
EINECS	Contact for details

Quality Control

Our production of Oxirane, (2-Methoxyphenyl)-, (-)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques including chiral HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment, supporting cGMP and ISO 9001 compliant workflows for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Refractive Index	Contact for details
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.