Description

6-(2,4-Dichlorophenyl)-Erythro-2,4-Dihydroxyhexylphosphonic Acid is a specialized organophosphorus compound with a unique stereochemical configuration. This compound serves as a critical intermediate in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where its specific structure imparts valuable biological activity. It is essential for research and development chemists working on novel active ingredients, including bisphosphonate derivatives and other therapeutic or crop protection agents. The compound's defined erythro configuration is crucial for achieving targeted efficacy in final applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel bisphosphonate drugs targeting bone disorders and other metabolic diseases.
• Agrochemical Research: Used in developing advanced herbicides and plant growth regulators that leverage its phosphonic acid moiety.
• Chemical Synthesis: Serves as a chiral synthon in asymmetric synthesis for creating complex molecules with specific stereocenters.
• Biochemical Probes: Utilized in research to study enzyme inhibition and metabolic pathways involving phosphonate analogs.
• Coordination Chemistry: Acts as a ligand for metal ions in catalytic systems or material science applications.

Basic Information

Product Name	6-(2,4-Dichlorophenyl)-Erythro-2,4-Dihydroxyhexylphosphonic Acid
CAS No.	141263-54-9
Molecular Formula	C12H17Cl2O5P
Molecular Weight	343.14 g/mol
Synonyms	(2R,4S)-6-(2,4-Dichlorophenyl)-2,4-dihydroxyhexylphosphonic acid; Erythro-6-(2,4-dichlorophenyl)-2,4-dihydroxyhexylphosphonic acid; (Erythro)-2,4-Dihydroxy-6-(2,4-dichlorophenyl)hexylphosphonic acid; 2,4-Dihydroxy-6-(2,4-dichlorophenyl)hexylphosphonic Acid (erythro-); Phosphonic acid, P-[6-(2,4-dichlorophenyl)-2,4-dihydroxyhexyl]-, (2R,4S)-
EINECS	Contact for details

Quality Control

Our 6-(2,4-Dichlorophenyl)-Erythro-2,4-Dihydroxyhexylphosphonic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, assay, impurity profile, and chiral excess are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (Erythro)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.