Description

1-Cyclopropyl-3-[2-(Methylsulfonyl)-4-(Trifluoromethyl)Phenyl]-1,3-Propanedione is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethyl and methylsulfonyl functional groups. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents, leveraging the trifluoromethyl group for improved efficacy and environmental profile.
• Chemical Research: Serves as a versatile scaffold in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Material Science: Potential application in the synthesis of specialty polymers and advanced materials requiring specific fluorinated components.

Basic Information

Product Name	1-Cyclopropyl-3-[2-(Methylsulfonyl)-4-(Trifluoromethyl)Phenyl]-1,3-Propanedione
CAS No.	141112-23-4
Molecular Formula	C14H13F3O4S
Molecular Weight	334.31 g/mol
Synonyms	1-Cyclopropyl-3-[2-(methylsulfonyl)-4-(trifluoromethyl)phenyl]propane-1,3-dione; 1,3-Propanedione, 1-cyclopropyl-3-[2-(methylsulfonyl)-4-(trifluoromethyl)phenyl]-; 141112-23-4; 2-(Methylsulfonyl)-4-(trifluoromethyl)benzoylcyclopropyl ketone; Cyclopropyl 2-(methylsulfonyl)-4-(trifluoromethyl)benzoyl ketone
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-3-[2-(Methylsulfonyl)-4-(Trifluoromethyl)Phenyl]-1,3-Propanedione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.