Description

1-Piperidinecarboxaldehyde, 4-Mercapto- (9Ci) is a specialized heterocyclic building block featuring both aldehyde and thiol functional groups on a piperidine scaffold. This unique bifunctional structure makes it a valuable intermediate for the synthesis of complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients, particularly in medicinal chemistry for creating targeted libraries. The compound, with CAS No. 141048-05-7, offers versatility for constructing diverse molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing potential drug candidates, especially in areas targeting neurological disorders and enzyme inhibition.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides due to its reactive thiol and aldehyde groups.
• Ligand Synthesis: Serves as a precursor for creating chelating ligands in catalysis and material science.
• Peptidomimetics & Bio-conjugation: The thiol group enables site-specific conjugation (e.g., for antibody-drug conjugates), while the aldehyde allows for reductive amination strategies.
• Chemical Library Development: A versatile scaffold for generating diverse compound libraries in high-throughput screening and medicinal chemistry programs.
• Material Science Precursor: Potential use in synthesizing functionalized polymers or surface modifiers.

Basic Information

Product Name	1-Piperidinecarboxaldehyde, 4-Mercapto- (9Ci)
CAS No.	141048-05-7
Molecular Formula	C7H11NOS
Molecular Weight	157.23 g/mol
Synonyms	4-Mercaptopiperidine-1-carboxaldehyde; 4-Thiolpiperidine-1-carboxaldehyde; 1-Formyl-4-mercaptopiperidine; 4-Mercapto-1-piperidinecarboxaldehyde; 4-Sulfanylpiperidine-1-carbaldehyde; 4-Piperidinethiol-1-carboxaldehyde; NSC 339586
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarboxaldehyde, 4-Mercapto- (9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material suitable for use under cGMP conditions for non-clinical research upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided. Keep the container in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.