Description

Serine, o-Methyl-, 1-Methylethyl Ester is a specialized amino acid derivative, specifically an ester of O-methylserine. This compound serves as a valuable protected serine building block in advanced organic synthesis, offering precise control over molecular structure and reactivity. It is primarily required by pharmaceutical R&D and fine chemical synthesis teams for developing novel peptides, active pharmaceutical ingredients (APIs), and complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Peptide Chemistry: Used as a protected serine residue in solid-phase and solution-phase peptide synthesis to prevent unwanted side reactions.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators with specific chiral centers.
• Bioconjugation & Probe Development: Utilized in the creation of labeled compounds, molecular probes, and antibody-drug conjugates (ADCs) for diagnostic and therapeutic applications.
• Academic & Industrial R&D: Employed in research laboratories for methodological development in asymmetric synthesis and organocatalysis.
• Flavor & Fragrance Precursor: Acts as an intermediate in the synthesis of certain specialty aroma chemicals.

Basic Information

Product Name	Serine, o-Methyl-, 1-Methylethyl Ester
CAS No.	140887-43-0
Molecular Formula	C7H15NO3
Molecular Weight	161.20 g/mol
Synonyms	L-Serine, O-methyl-, 1-methylethyl ester; Isopropyl O-methyl-L-serinate; O-Methyl-L-serine isopropyl ester; (2S)-2-Amino-3-methoxypropanoic acid 1-methylethyl ester; L-O-Methylserine isopropyl ester; Protected Serine isopropyl ester; Serine methyl ether isopropyl ester
EINECS	Contact for details

Quality Control

Our Serine, o-Methyl-, 1-Methylethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and chiral integrity, meeting the exacting standards required for synthetic chemistry applications. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Optical Rotation [α]D20	Contact for details
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.