Description

Propanoic Acid, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-3-Hydroxy- (9Ci) is a specialized amino acid derivative with a protected amine group, offering a versatile building block for advanced organic synthesis. This compound is valued for its role in introducing chiral centers and functional complexity into target molecules, enabling the development of high-value fine chemicals and active pharmaceutical ingredients (APIs). It is primarily sought by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel APIs, particularly in the development of peptidomimetics, enzyme inhibitors, and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators that require specific stereochemistry.
• Peptide Chemistry: Serves as a protected amino acid derivative for solid-phase and solution-phase peptide synthesis, facilitating the creation of custom peptide sequences.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for asymmetric synthesis applications.
• Bioconjugation and Linker Chemistry: Useful for creating functionalized linkers in antibody-drug conjugates (ADCs) and other bioconjugation strategies.
• Academic and Industrial R&D: A valuable reagent for methodological development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	Propanoic Acid, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-3-Hydroxy- (9Ci)
CAS No.	140686-90-4
Molecular Formula	C9H17NO5
Molecular Weight	219.24 g/mol
Synonyms	3-[(tert-Butoxycarbonyl)amino]-3-hydroxypropanoic acid; 3-[(Boc)amino]-3-hydroxypropanoic acid; 3-Hydroxy-3-[(tert-butoxycarbonyl)amino]propanoic acid; Boc-NH-CH(OH)-CH2-COOH; (R/S)-3-((tert-Butoxycarbonyl)amino)-3-hydroxypropanoic acid; 3-Amino-3-hydroxypropanoic acid Boc derivative; β-Hydroxy-β-(Boc-amino)propionic acid
EINECS	Contact for details

Quality Control

Our Propanoic Acid, 3-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-3-Hydroxy- (9Ci) is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure high chemical and isomeric purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.