Description

3-Cyano-Benzamidine is a high-purity organic building block and versatile chemical intermediate of significant importance in modern synthetic chemistry. Its unique bifunctional structure, containing both a cyano group and an amidine moiety, makes it a critical precursor for the synthesis of complex heterocycles and pharmacologically active compounds. This compound is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers focused on creating novel molecules for drug discovery and advanced material science.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of protease inhibitors, kinase inhibitors, and other small molecule therapeutics.
• Heterocyclic Chemistry: Used in the construction of pyrimidines, triazines, and other nitrogen-containing heterocycles prevalent in agrochemicals and pharmaceuticals.
• Chemical Biology & Proteomics: Serves as a precursor for activity-based probes and affinity labels targeting serine proteases and other enzymes.
• Material Science Research: Employed in the development of novel polymers and organic frameworks with specific binding properties.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name	3-Cyano-Benzamidine
CAS No.	140658-21-5
Molecular Formula	C8H7N3
Molecular Weight	145.16 g/mol
Synonyms	3-Cyanobenzamidine; m-Cyanobenzamidine; Benzenecarboximidamide, 3-cyano-; 3-Cyano-benzenecarboximidamide; 3-Cyanophenylamidine; m-Cyanophenylamidine; (3-Cyanophenyl)methanimidamide; 140658-21-5
EINECS	Contact for details

Quality Control

Our 3-Cyano-Benzamidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all specifications and test results to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.