Description

Propanoic Acid, 2-Fluoro-2-Nitro-, Ethyl Ester (9Ci) is a specialized fluorinated nitro ester building block of significant interest in advanced organic synthesis. Its unique structure, featuring both fluorine and nitro functional groups on the same carbon, makes it a valuable precursor for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the fluorine atom can improve biological activity and environmental persistence.
• Organic Synthesis Reagent: Serves as a versatile electrophile or a precursor for other functional groups (like amines or carbonyls) in multi-step synthetic routes for complex molecules.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or liquid crystals where the introduction of fluorine can alter material properties such as solubility and thermal stability.
• Fluorine Chemistry Studies: Employed in academic and industrial research to study the reactivity and effects of gem-difluoro and nitro-substituted carbon centers.

Basic Information

Product Name	Propanoic Acid, 2-Fluoro-2-Nitro-, Ethyl Ester (9Ci)
CAS No.	140427-78-7
Molecular Formula	C5H8FNO4
Molecular Weight	165.12 g/mol
Synonyms	Ethyl 2-Fluoro-2-nitropropanoate; 2-Fluoro-2-nitropropionic Acid Ethyl Ester; Ethyl 2-Fluoro-2-nitropropionate; NSC 405124; Propanoic acid, 2-fluoro-2-nitro-, ethyl ester; 2-Nitro-2-fluoropropionic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Propanoic Acid, 2-Fluoro-2-Nitro-, Ethyl Ester (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and spectroscopic identification, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material should be stored separately from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.