Description

2-Hydroxysuccinic Acid Methyl Ester is a versatile chiral building block and intermediate in fine chemical synthesis. Its value lies in its bifunctional structure, containing both a hydroxyl and an ester group, which facilitates its use in the production of more complex molecules. This compound is particularly relevant for manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop enantiomerically pure products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring specific stereochemistry.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where stereoselectivity impacts biological activity.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other high-value specialty chemicals.
• Polymer Modification: Acts as a monomer or co-monomer in the synthesis of biodegradable or functional polymers.
• Ligand and Catalyst Preparation: Utilized in the development of chiral ligands for asymmetric catalysis.
• Research & Development: A valuable compound for organic synthesis research in academic and industrial laboratories.

Basic Information

Product Name	2-Hydroxysuccinic Acid Methyl Ester
CAS No.	140235-34-3
Molecular Formula	C5H8O5
Molecular Weight	148.11 g/mol
Synonyms	Methyl 2-Hydroxysuccinate; Methyl DL-Malate; Methyl Hydroxybutanedioate; DL-Malic Acid Monomethyl Ester; Methyl 2-Hydroxybutanedioate; 2-Hydroxybutanedioic Acid Monomethyl Ester; Methyl (DL)-Malate; Monomethyl Malate
EINECS	Contact for details

Quality Control

Our 2-Hydroxysuccinic Acid Methyl Ester is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure it meets the required chemical and chiral purity specifications for its intended application. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	Specify required enantiomeric excess (ee)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.