Description

2,3,4,6-Tetra-o-Acetyl-D-Mannopyranose is a key acetylated monosaccharide derivative, serving as a vital protected intermediate in synthetic organic chemistry. Its primary value lies in enabling the controlled synthesis of complex carbohydrates, glycoconjugates, and other bioactive molecules where selective deprotection is required. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors developing novel therapeutics, diagnostics, and advanced materials.

Application

• Glycosylation Intermediate: A crucial protected precursor for the synthesis of oligosaccharides, glycopeptides, and glycolipids.
• Pharmaceutical API Synthesis: Used in the research and development of carbohydrate-based active pharmaceutical ingredients (APIs) and prodrugs.
• Glycoconjugate Production: Serves as a building block for creating vaccines, diagnostic reagents, and targeted drug delivery systems.
• Chemical Biology Research: Employed in the study of carbohydrate-protein interactions and enzymatic processes.
• Fine Chemical Synthesis: Acts as a chiral starting material or intermediate for synthesizing specialty chemicals and flavors.
• Standards and Reference Materials: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2,3,4,6-Tetra-o-Acetyl-D-Mannopyranose
CAS No.	140147-37-1
Molecular Formula	C14H20O10
Molecular Weight	348.30 g/mol
Synonyms	1,2,3,4,6-Penta-O-acetyl-D-mannopyranose (common misnomer); D-Mannose pentaacetate; α-D-Mannopyranose pentaacetate; Penta-O-acetyl-α-D-mannopyranose; Acetylated D-Mannose; Mannose Pentaacetate; Tetraacetyl Mannose; 2,3,4,6-Tetra-O-acetyl-α-D-mannopyranosyl chloride precursor
EINECS	Contact for details

Quality Control

Our 2,3,4,6-Tetra-o-Acetyl-D-Mannopyranose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and specific tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications and results is provided with every shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Specific Rotation	Contact for details
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.