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1-[2-(1-Hydroxycyclopropyl)Ethyl]Cyclopropanol CAS NO 139963-74-9


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CAS No.:139963-74-9

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1-[2-(1-Hydroxycyclopropyl)Ethyl]Cyclopropanol is a specialized bifunctional cyclopropane derivative featuring two hydroxyl groups, making it a valuable synthon in advanced organic synthesis. This compound's unique strained-ring structure and dual reactivity are critical for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical and life sciences industries for applications requiring precise stereochemistry and ring-strain energy.

Application

  • Pharmaceutical Intermediate: A key building block for synthesizing novel active pharmaceutical ingredients (APIs), especially those containing cyclopropane motifs known for metabolic stability.
  • Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the cyclopropane ring enhances biological activity.
  • Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
  • Material Science Research: Employed in the creation of novel monomers and polymers with specific thermal or mechanical properties derived from the strained ring system.
  • Cross-Coupling Reactions: Functions as a versatile substrate in palladium-catalyzed and other metal-mediated coupling reactions to create complex carbon skeletons.
  • Protecting Group Strategy: The hydroxyl groups can be selectively protected and deprotected, enabling sophisticated multi-step synthetic pathways.

Basic Information

Product Name 1-[2-(1-Hydroxycyclopropyl)Ethyl]Cyclopropanol
CAS No. 139963-74-9
Molecular Formula C8H14O2
Molecular Weight 142.20 g/mol
Synonyms 1-[2-(1-Hydroxycyclopropyl)ethyl]cyclopropanol; 1,1'-[1,2-Ethanediylbis(cyclopropane-1,1-diyl)]dimethanol; Bicyclopropanol derivative; 1,1'-(Ethane-1,2-diyl)bis(cyclopropan-1-ol); 1,1'-Ethylenebis(cyclopropanol); 1,2-Bis(1-hydroxycyclopropyl)ethane; Cyclopropanol, 1,1'-(1,2-ethanediyl)bis-
EINECS Contact for details

Quality Control

Every batch of 1-[2-(1-Hydroxycyclopropyl)Ethyl]Cyclopropanol is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by techniques such as HPLC, GC, and NMR is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Melting Point Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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