Description

Cyclopropanecarboxylic Acid, 1-Amino-2-(3-Hydroxyphenyl)-, (1S-Trans)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its unique structure, featuring both amino and phenolic hydroxyl functional groups on a cyclopropane scaffold, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging the biological activity of the cyclopropane and aminophenol motifs.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands used in asymmetric catalysis, enabling the production of enantiomerically pure compounds.
• Chemical Research: Employed in academic and industrial R&D for studying cyclopropane ring chemistry and for synthesizing specialized libraries of compounds for screening.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex, high-value fine chemicals and specialty materials.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-Amino-2-(3-Hydroxyphenyl)-, (1S-Trans)- (9Ci)
CAS No.	139561-06-1
Molecular Formula	C10H11NO3
Molecular Weight	193.20 g/mol
Synonyms	(1S,2S)-1-Amino-2-(3-hydroxyphenyl)cyclopropanecarboxylic acid; (1S-trans)-1-Amino-2-(3-hydroxyphenyl)cyclopropanecarboxylic Acid; 1-Amino-2-(3-hydroxyphenyl)cyclopropanecarboxylic acid, (1S,2S)-; 2-(3-Hydroxyphenyl)-1-aminocyclopropanecarboxylic acid; UNII-9K5N8V3I1H; 9K5N8V3I1H; A chiral cyclopropane amino acid derivative
EINECS	Contact for details

Quality Control

Every batch of Cyclopropanecarboxylic Acid, 1-Amino-2-(3-Hydroxyphenyl)-, (1S-Trans)- (9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity consistent with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.