Description

3-(3-Chlorophenyl)-1,1,1-Trifluoro-2-Propanone is a versatile fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its core value lies in the unique reactivity imparted by the trifluoromethyl ketone group adjacent to an aromatic chlorophenyl ring, enabling precise molecular construction. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to incorporate trifluoromethyl motifs into complex molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of novel herbicides and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic materials with tailored properties.
• Fluorine Chemistry Studies: A valuable substrate for investigating novel fluorination reactions and the behavior of fluorinated functional groups.

Basic Information

Product Name	3-(3-Chlorophenyl)-1,1,1-Trifluoro-2-Propanone
CAS No.	139521-25-8
Molecular Formula	C9H6ClF3O
Molecular Weight	222.59 g/mol
Synonyms	1-(3-Chlorophenyl)-3,3,3-trifluoro-2-propanone; 3-Chloro-α,α,α-trifluoroacetophenone; 3'-Chloro-α,α,α-trifluoroacetophenone; 3-Chlorophenyl trifluoromethyl ketone; m-Chloro-α,α,α-trifluoroacetophenone; 3,3,3-Trifluoro-1-(3-chlorophenyl)-2-propanone; 139521-25-8; 3-(3-Chlorophenyl)-1,1,1-trifluoropropan-2-one
EINECS	Contact for details

Quality Control

Our 3-(3-Chlorophenyl)-1,1,1-Trifluoro-2-Propanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.