Description

Pyrimidine, 5-(Diethylboryl)- (9Ci) is a specialized organoboron derivative of the pyrimidine heterocycle, a key structural motif in many bioactive compounds. This compound serves as a valuable synthetic intermediate and building block in advanced organic synthesis, particularly for introducing boron-containing functional groups. It is primarily utilized by research institutions and industrial R&D departments focused on developing novel materials and pharmaceuticals, including potential applications in medicinal chemistry and materials science.

Application

• Pharmaceutical Intermediate: Used in the research and synthesis of novel drug candidates, particularly in boron neutron capture therapy (BNCT) and other targeted therapeutic agents.
• Advanced Material Synthesis: Serves as a key precursor for creating boron-doped organic electronic materials, polymers, and liquid crystals.
• Cross-Coupling Reactions: Acts as an organoboron reagent (boronic acid ester analog) in Suzuki-Miyaura and other transition metal-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Chemical Research: Employed in academic and industrial laboratories for studying the reactivity and properties of heterocyclic organoboron compounds.
• Ligand Development: Potential use in the development of novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Pyrimidine, 5-(Diethylboryl)- (9Ci)
CAS No.	139298-13-8
Molecular Formula	C8H13BN2
Molecular Weight	148.02 g/mol
Synonyms	5-(Diethylboryl)pyrimidine; Diethyl(5-pyrimidinyl)borane; 5-Diethylborylpyrimidine; Pyrimidine-5-boronic acid diethyl ester; (5-Pyrimidinyl)diethylborane; 139298-13-8; 5-Pyrimidyldiethylborane
EINECS	Contact for details

Quality Control

Our Pyrimidine, 5-(Diethylboryl)- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR (¹H, ¹¹B, ¹³C), HPLC for purity assessment, and FT-IR for structural confirmation, to ensure consistency and high chemical integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We support custom synthesis and can tailor purity grades to meet specific research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being easily oxidized and hygroscopic, this material must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep the container tightly sealed in a desiccator to minimize exposure to moisture and oxygen.

Specification

Item	Specification
Appearance	White to off-white solid or crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Research Grade)
¹H NMR Purity	Conforms
¹¹B NMR	Conforms
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.