Description

14-Hydroxy-4,14-Retro-Retinol is a specialized retinoid derivative, a key synthetic intermediate in the production of advanced pharmaceutical compounds. This compound matters for its precise molecular structure, which is engineered to interact with specific biological pathways, offering researchers and manufacturers a critical building block for novel therapeutics. It is primarily needed by R&D laboratories and pharmaceutical companies focused on developing next-generation dermatological treatments, oncology drugs, and other targeted therapies where retinoid signaling is crucial.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel retinoid-based drugs targeting skin conditions, cancer, and metabolic disorders.
• Dermatological Research: Used in the development of advanced topical formulations for anti-aging, acne, and psoriasis treatments due to its modified retinoid activity.
• Biochemical Research: A valuable tool for studying retinoid metabolism, receptor binding (RAR/RXR), and gene expression regulation in cellular models.
• Cosmeceutical Development: Employed in high-end R&D for creating next-generation cosmetic active ingredients with enhanced stability and targeted efficacy.
• Chemical Synthesis: Acts as a specialized synthon for constructing complex organic molecules with specific stereochemistry for medicinal chemistry applications.

Basic Information

Product Name	14-Hydroxy-4,14-Retro-Retinol
CAS No.	139257-77-5
Molecular Formula	C20H30O2
Molecular Weight	302.45 g/mol
Synonyms	4,14-Retro-Retinol, 14-Hydroxy-; 14-Hydroxyretro-retinol; (3E,5E,7E,9E,11E,13E)-3,7,12,16-Tetramethyl-1-(2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl)hexadeca-3,5,7,9,11,13-hexaen-14-ol; 14-Hydroxy-4,14-retro-retinol; Retro-14-hydroxyretinol; All-trans-14-hydroxy-4,14-retro-retinol
EINECS	Contact for details

Quality Control

Our 14-Hydroxy-4,14-Retro-Retinol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.