Description

21-Oxolup-18-Ene-3-Beta,28-Diyldiacetate is a high-purity, semi-synthetic lupane-type triterpenoid derivative. This compound serves as a critical intermediate and reference standard in advanced pharmaceutical research and development, particularly for investigating bioactive natural product analogs. It is primarily utilized by research institutions and pharmaceutical companies focused on developing novel therapeutic agents, especially in the fields of oncology, anti-inflammatory, and antiviral drug discovery.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel lupane-based drug candidates with potential anti-cancer and anti-inflammatory properties.
• Reference Standard: Used in analytical laboratories for the qualitative and quantitative analysis of complex natural product extracts and synthetic mixtures via HPLC, LC-MS, or NMR.
• Biochemical Research: Employed in academic and industrial research to study structure-activity relationships (SAR) of triterpenoids and their interactions with biological targets.
• Natural Product Synthesis: Serves as a versatile building block in the semi-synthesis of more complex, biologically active triterpenoid derivatives for screening programs.
• Quality Control: Acts as a certified reference material (CRM) for ensuring the purity and consistency of related active pharmaceutical ingredients (APIs) during manufacturing.

Basic Information

Item	Details
Product Name	21-Oxolup-18-Ene-3-Beta,28-Diyldiacetate
CAS No.	139255-65-5
Molecular Formula	C34H50O5
Molecular Weight	538.77 g/mol
Synonyms	3β,28-Diacetoxy-21-oxolup-18-ene; 21-Oxo-18-lupene-3β,28-diyl diacetate; Lup-18-ene-3,28-diol, 21-oxo-, 3,28-diacetate; 21-Oxobetulin diacetate; 3β,28-Diacetyl-21-oxolup-18-ene; Betulin derivative 21-oxo diacetate; (3β)-21-Oxolup-18-ene-3,28-diyl diacetate
EINECS	Contact for details

Quality Control

Our 21-Oxolup-18-Ene-3-Beta,28-Diyldiacetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.