Description

1-Aza-2,5-Disilacyclopentane-1-Acetic Acid, -α-,2,2,5,5-Pentamethyl-, 2-Bromoethyl Ester, (S)- (9Ci) is a high-value, chiral organosilicon compound that serves as a sophisticated building block in advanced synthetic chemistry. Its unique structure, featuring a silicon-nitrogen heterocycle and a bromoethyl ester handle, makes it a critical precursor for constructing complex molecules with precise stereochemistry. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, chiral catalysts, and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Organosilicon Chemistry: Serves as a versatile precursor for the preparation of novel sila-heterocycles and functionalized silicon-containing polymers.
• Chiral Ligand & Catalyst Development: Employed in the design and synthesis of new chiral ligands for asymmetric catalysis, enhancing enantioselectivity in critical bond-forming reactions.
• Material Science Research: Investigated for incorporation into hybrid organic-inorganic materials (OIMs) and advanced coatings with tailored properties.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in synthetic organic and organometallic chemistry at universities and corporate R&D centers.

Basic Information

Item	Details
Product Name	1-Aza-2,5-Disilacyclopentane-1-Acetic Acid, -α-,2,2,5,5-Pentamethyl-, 2-Bromoethyl Ester, (S)- (9Ci)
CAS No.	139215-50-2
Molecular Formula	C12H26BrNO2Si2
Molecular Weight	352.42 g/mol
Synonyms	(S)-2-Bromoethyl 2-(2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopent-1-yl)propanoate; (S)-2-Bromoethyl α-(2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopentan-1-yl)propionate; 2-Bromoethyl (S)-2-(2,2,5,5-tetramethyl-1-aza-2,5-disilacyclopent-1-yl)propanoate; 1-Aza-2,5-disilacyclopentane-1-acetic acid, α,2,2,5,5-pentamethyl-, 2-bromoethyl ester, (S)-; Bromoethyl ester of (S)-pentamethyl-1-aza-2,5-disilacyclopentane-1-acetic acid; Chiral azadisilacyclopentane bromoester; Silicon-nitrogen heterocycle bromoethyl ester
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and analyzed under strict quality protocols to ensure high purity and lot-to-lot consistency, critical for sensitive synthetic applications. Our quality system ensures compliance with relevant standards for research chemicals. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity (typically by HPLC/NMR), chiral purity, and identification data.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container for use to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.