Description

2-(2-Boc-Aminoethoxy)Ethanol is a versatile bifunctional chemical building block featuring both a protected amine group and a terminal hydroxyl group. This compound is critical for the controlled synthesis of complex molecules, offering orthogonal reactivity for sequential functionalization. It is primarily utilized by researchers and manufacturers in the pharmaceutical and biotechnology sectors for applications such as linker chemistry, polymer modification, and the development of prodrugs and targeted delivery systems.

Application

• Pharmaceutical Intermediates: A key synthon for constructing peptide mimetics, antibody-drug conjugates (ADCs), and other bioactive molecules.
• Linker Chemistry: Used in the design and synthesis of cleavable or non-cleavable linkers for bioconjugation and drug delivery platforms.
• Polymer Functionalization: Serves as a monomer or modifier for creating functionalized polyethylene glycol (PEG) derivatives and other specialty polymers.
• Prodrug Synthesis: Enables the attachment of solubilizing or targeting groups to active pharmaceutical ingredients (APIs) via its hydroxyl terminus.
• Surface Modification: Used to introduce amine-reactive sites onto materials and nanoparticles after Boc deprotection.
• Chemical Biology Tools: Employed in the synthesis of probes, tags, and reagents for studying biological processes.

Basic Information

Product Name	2-(2-Boc-Aminoethoxy)Ethanol
CAS No.	139115-91-6
Molecular Formula	C9H19NO5
Molecular Weight	221.25 g/mol
Synonyms	2-[2-[(tert-Butoxycarbonyl)amino]ethoxy]ethanol; 2-(2-((tert-Butoxycarbonyl)amino)ethoxy)ethan-1-ol; N-Boc-2-aminoethoxyethanol; 2-(2-(Boc-amino)ethoxy)ethanol; Ethanol, 2-[2-[(1,1-dimethylethoxy)carbonyl]amino]ethoxy]-; Boc-NH-PEG2-OH; tert-Butyl N-(2-(2-hydroxyethoxy)ethyl)carbamate
EINECS	Contact for details

Quality Control

Our 2-(2-Boc-Aminoethoxy)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance for sensitive synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research and cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The product is hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.