Description

2-Bromo-2-Fluoro-3-Oxo-3-Phenyl-Propionic Acid Ethyl Ester is a high-value fluorinated and brominated building block with significant synthetic utility. This compound is essential for advanced organic synthesis, particularly in the construction of complex molecules for pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, including protease inhibitors and other bioactive molecules.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging the unique properties of fluorine and bromine atoms.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers with tailored properties.
• Organic Synthesis Building Block: Employed in various name reactions (e.g., Reformatsky-type reactions, nucleophilic substitutions) to introduce both fluorine and bromine functional groups.
• Fluorine Chemistry Research: A valuable substrate for studying the reactivity and stability of α-fluoro-α-bromo carbonyl compounds.
• Ligand and Catalyst Development: Potential use in synthesizing novel chiral ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	2-Bromo-2-Fluoro-3-Oxo-3-Phenyl-Propionic Acid Ethyl Ester
CAS No.	139101-23-8
Molecular Formula	C11H10BrFO3
Molecular Weight	289.10 g/mol
Synonyms	Ethyl 2-Bromo-2-fluoro-3-oxo-3-phenylpropanoate; Ethyl α-Bromo-α-fluoro-β-oxo-β-phenylpropionate; 2-Bromo-2-fluoro-3-oxo-3-phenylpropionic acid ethyl ester; 139101-23-8; Ethyl 2-bromo-2-fluoro-3-oxo-3-phenylpropionate; β-Oxo-β-phenyl-α-bromo-α-fluoropropionic acid ethyl ester; NSC 405124; AI3-52210
EINECS	Contact for details

Quality Control

Our production of 2-Bromo-2-Fluoro-3-Oxo-3-Phenyl-Propionic Acid Ethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by modern analytical techniques including NMR, HPLC, and GC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.