Description

(R)-(+)-4-Hexyl-2,2-Dimethyl-1,3-Dioxane is a high-purity chiral building block and specialty solvent critical for advanced organic synthesis. Its value lies in its well-defined stereochemistry and the protective acetal functionality, enabling precise chemical transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fragrance industries who require enantiomerically pure intermediates for developing active ingredients and fine chemicals.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: Serves as a key precursor for the development of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in asymmetric synthesis.
• Agrochemical Research & Development: Used in the creation of novel, stereospecific pesticides and herbicides where biological activity is often chirality-dependent.
• Specialty Solvent for Sensitive Reactions: Acts as a protective, aprotic solvent medium for reactions requiring anhydrous conditions and stability of acid-sensitive groups.
• Fragrance and Flavor Chemistry: Employed as a building block for synthesizing specific, high-value odorants and flavor compounds with defined stereocenters.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, catalysis, and material science research.
• Liquid Crystal and Advanced Material Precursor: Potential use in the synthesis of chiral dopants and organic components for advanced material applications.

Basic Information

Product Name	(R)-(+)-4-Hexyl-2,2-Dimethyl-1,3-Dioxane
CAS No.	139008-49-4
Molecular Formula	C₁₂H₂₄O₂
Molecular Weight	200.32 g/mol
Synonyms	(R)-4-Hexyl-2,2-dimethyl-1,3-dioxane; (+)-4-Hexyl-2,2-dimethyl-1,3-dioxane; (R)-(+)-4-n-Hexyl-2,2-dimethyl-1,3-dioxolane (common misnomer); 1,3-Dioxane, 4-hexyl-2,2-dimethyl-, (4R)-; (4R)-4-Hexyl-2,2-dimethyl-1,3-dioxane; Chiral hexyl dioxane; DIOXANE-C6 (R); (R)-enantiomer of 4-hexyl-2,2-dimethyl-1,3-dioxane
EINECS	Contact for details

Quality Control

Our (R)-(+)-4-Hexyl-2,2-Dimethyl-1,3-Dioxane is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC or GC, to ensure high enantiomeric excess (e.e.) and chemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.