Description

Dehydroandrographolide 6-Succinic Acid Monoester is a chemically modified derivative of the bioactive diterpenoid lactone, dehydroandrographolide, which is a key constituent of the medicinal herb Andrographis paniculata. This semi-synthetic compound is valued for its enhanced solubility profile and potential for improved bioavailability, making it a critical intermediate for advanced pharmaceutical research and development. It is primarily sought by manufacturers and R&D laboratories in the pharmaceutical, nutraceutical, and fine chemical sectors for developing novel therapeutic agents and high-purity reference standards.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel anti-inflammatory, antiviral, and hepatoprotective drug candidates.
• Reference Standard: Used as a high-purity certified reference material (CRM) for quality control and analytical method development in laboratories.
• Nutraceutical Research: Investigated for the development of advanced dietary supplements with targeted bioactivity.
• Biochemical Research: Employed in pharmacological and metabolic studies to understand structure-activity relationships (SAR) of andrographolide derivatives.
• Fine Chemical Synthesis: Serves as a specialized intermediate for creating custom derivatives and conjugates for various research applications.

Basic Information

Item	Detail
Product Name	Dehydroandrographolide 6-Succinic Acid Monoester
CAS No.	138898-71-2
Molecular Formula	C26H34O8
Molecular Weight	474.55 g/mol
Synonyms	Dehydroandrographolide Succinate; Dehydroandrographolide 6-Hydrogen Succinate; 14-Deoxy-11,12-didehydroandrographolide 6-succinate; 3-[2-[Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone 6-(3-carboxypropanoate); Andrographolide derivative 6-succinic acid ester
EINECS	Contact for details

Quality Control

Our Dehydroandrographolide 6-Succinic Acid Monoester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.