Description

Z-Val-Gly-Phe-Oh CAS NO 138867-42-2 is a synthetic tripeptide derivative featuring a C-terminal carboxylic acid and an N-terminal Z-protected (benzyloxycarbonyl) valine residue. This compound serves as a crucial protected peptide building block in solid-phase and solution-phase peptide synthesis, enabling the controlled elongation of peptide chains. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers for developing therapeutic peptides, biochemical probes, and advanced materials.

Application

• Pharmaceutical Intermediate: Key raw material for the synthesis of longer, biologically active peptide sequences for drug discovery and development.
• Biochemical Research: Used as a standard or reagent in proteomics and enzymology studies to investigate peptide structure and function.
• Peptide Library Synthesis: Essential component in combinatorial chemistry for creating diverse peptide libraries for screening against biological targets.
• Custom Peptide Production: Building block for contract research and manufacturing organizations (CROs/CMOs) producing bespoke peptides for clients.
• Academic Research: Employed in university and institutional labs for teaching advanced peptide chemistry and conducting fundamental research.
• Material Science: Potential precursor for designing peptide-based polymers, hydrogels, or surface coatings with specific properties.

Basic Information

Item	Details
Product Name	Z-Val-Gly-Phe-Oh
CAS No.	138867-42-2
Molecular Formula	C24H29N3O6
Molecular Weight	455.51 g/mol
Synonyms	N-Benzyloxycarbonyl-L-valylglycyl-L-phenylalanine; Z-L-Val-Gly-L-Phe-OH; N-Cbz-L-valyl-glycyl-L-phenylalanine; Benzyloxycarbonyl-Val-Gly-Phe; Cbz-Val-Gly-Phe-OH; Z-Val-Gly-Phe; (S)-2-(((S)-1-((Benzyloxy)carbonyl)-2-methylpropyl)amino)-2-oxoethyl)-2-((S)-2-amino-3-phenylpropanamido)acetate; Nα-Carbobenzoxy-L-valyl-glycyl-L-phenylalanine
EINECS	Contact for details

Quality Control

Our Z-Val-Gly-Phe-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS), to ensure it meets stringent specifications for peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.