Description

Bis(T-Butylsulfonyl)Diazomethane is a versatile and highly reactive diazo transfer reagent used in organic synthesis. This compound matters for its ability to efficiently introduce diazo functional groups under mild conditions, enabling key transformations in complex molecule construction. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for applications ranging from API synthesis to polymer modification.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for the preparation of diazo compounds used in the synthesis of active pharmaceutical ingredients (APIs) and complex heterocycles.
• Agrochemical Development: Employed in the research and production of novel pesticides and herbicides, facilitating the construction of specific bioactive scaffolds.
• Polymer & Material Science: Used as a cross-linking agent or to introduce reactive sites into polymer chains for specialty material development.
• Organic Methodology Research: A crucial tool in academic and industrial R&D for developing new carbon-carbon and carbon-heteroatom bond-forming reactions via carbene or metal-carbenoid intermediates.
• Peptide Modification: Applied in bioconjugation chemistry for the selective labeling or functionalization of peptides and proteins.
• Catalyst & Ligand Synthesis: Used in the preparation of specialized metal-organic complexes and catalysts for asymmetric synthesis.

Basic Information

Product Name	Bis(T-Butylsulfonyl)Diazomethane
CAS No.	138529-84-7
Molecular Formula	C10H20N2O4S2
Molecular Weight	296.41 g/mol
Synonyms	Bis(tert-Butylsulfonyl)diazomethane; Di-tert-butylsulfonyldiazomethane; (Diazomethylene)bis(tert-butyl sulfone); 2-Diazo-2-[(2-methyl-2-propanyl)sulfonyl]-1,1-bis[(2-methyl-2-propanyl)sulfonyl]ethane; TBAD; DTBS diazomethane
EINECS	Contact for details

Quality Control

Our Bis(T-Butylsulfonyl)Diazomethane is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific research or cGMP starting material requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) or as specified on the label. This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.