Description

(4-Phthalimidomethylphenyl)Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and development.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl halides and this boronic ester, crucial for synthesizing biaryl structures found in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Used in the research and development of novel drug candidates, particularly in constructing complex, functionalized aromatic systems.
• Agrochemical Compound Development: Employed in creating new herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science & OLED Research: Acts as a precursor for synthesizing organic semiconductors, ligands for catalysts, and emissive layers in organic light-emitting diodes (OLEDs).
• Chemical Biology & Probe Development: Useful for labeling and modifying biomolecules or creating chemical probes for biological target identification.
• Scale-up Process Chemistry: The pinacol ester protection enhances stability, making this compound suitable for multi-step synthesis and larger-scale manufacturing processes.

Basic Information

Product Name	(4-Phthalimidomethylphenyl)Boronic Acid Pinacol Ester
CAS No.	138500-87-5
Molecular Formula	C22H24BNO4
Molecular Weight	377.25 g/mol
Synonyms	4-(Phthalimidomethyl)phenylboronic acid pinacol ester; [4-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-ylmethyl)phenyl]boronic acid pinacol ester; 2-{[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]}-1H-isoindole-1,3(2H)-dione; 4-Phthalimidomethylbenzeneboronic Acid Pinacol Ester; N-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]phthalimide
EINECS	Contact for details

Quality Control

Every batch of (4-Phthalimidomethylphenyl)Boronic Acid Pinacol Ester is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.