Description

4-(Cyanomethyl)Benzeneboronic Acid Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a crucial protected intermediate in modern organic synthesis, particularly for Suzuki-Miyaura cross-coupling reactions, enabling the construction of complex biaryl and heterobiaryl structures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality building blocks for drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific biaryl motifs.
• Material Science: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where precise molecular architecture is critical.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for biochemical research.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-(Cyanomethyl)Benzeneboronic Acid Pinacol Ester
CAS No.	138500-86-4
Molecular Formula	C14H18BNO2
Molecular Weight	243.11 g/mol
Synonyms	4-(Cyanomethyl)phenylboronic acid pinacol ester; (4-(Cyanomethyl)phenyl)boronic acid pinacol ester; 2-[4-(Cyanomethyl)phenyl]-5,5-dimethyl-1,3,2-dioxaborinane; 4-(Cyanomethyl)benzeneboronic acid, pinacol ester; 4-(Cyanomethyl)phenylboronic acid neopentyl glycol ester (common alternative); 4-(Cyanomethyl)benzeneboronic acid cyclic ester; p-Cyanomethylbenzeneboronic acid pinacol ester; B-[4-(Cyanomethyl)phenyl]-5,5-dimethyl-1,3,2-dioxaborinane
EINECS	Contact for details

Quality Control

Our 4-(Cyanomethyl)Benzeneboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.