Description

4-Formyl-2-Hydroxy-3-Iodoanisole is a versatile iodinated aromatic aldehyde building block of significant interest in advanced organic synthesis. Its unique structure, featuring formyl, hydroxy, and iodo substituents on an anisole ring, makes it a critical precursor for constructing complex molecular architectures. This high-purity intermediate is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science: Employed in the creation of functionalized polymers and advanced organic materials with specific electronic or optical properties.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Heck) and as a scaffold for further functionalization in custom synthesis projects.

Basic Information

Product Name	4-Formyl-2-Hydroxy-3-Iodoanisole
CAS No.	138490-94-5
Molecular Formula	C8H7IO3
Molecular Weight	278.05 g/mol
Synonyms	3-Iodo-4-hydroxy-5-methoxybenzaldehyde; 5-Methoxy-2-hydroxy-3-iodobenzaldehyde; 2-Hydroxy-3-iodo-5-methoxybenzaldehyde; 4-Hydroxy-3-iodo-5-methoxybenzaldehyde; 3-Iodo-5-methoxysalicylaldehyde
EINECS	Contact for details

Quality Control

Our 4-Formyl-2-Hydroxy-3-Iodoanisole is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.