Description

1-Propanone, 2-Chloro-1-(2,4-Difluorophenyl)- (9Ci) is a specialized fluorinated and chlorinated aromatic ketone building block, identified by CAS NO 138457-39-3. This compound is valued for its unique molecular structure, which makes it a critical intermediate in the synthesis of complex active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors for constructing novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of new drug candidates, particularly in antifungal and CNS-active therapeutic areas.
• Agrochemical Synthesis: Serves as a crucial building block for developing next-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Chemical Research & Development: Used in academic and industrial R&D labs for exploring novel organic reactions and synthesizing complex fluorinated compounds.
• Material Science Precursor: Potential intermediate in the synthesis of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	1-Propanone, 2-Chloro-1-(2,4-Difluorophenyl)- (9Ci)
CAS No.	138457-39-3
Molecular Formula	C9H5ClF2O
Molecular Weight	202.59 g/mol
Synonyms	2-Chloro-1-(2,4-difluorophenyl)propan-1-one; 2-Chloro-2',4'-difluoropropiophenone; 1-(2,4-Difluorophenyl)-2-chloropropan-1-one; 2-Chloro-1-(2,4-difluorophenyl)propanone; 2-Chloro-2',4'-difluoropropiophenone; α-Chloro-2',4'-difluoropropiophenone; Propanone, 2-chloro-1-(2,4-difluorophenyl)-
EINECS	Contact for details

Quality Control

Every batch of 1-Propanone, 2-Chloro-1-(2,4-Difluorophenyl)- (9Ci) is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the rigorous standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot and provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.