Description

2-Oxo-1-Pyrrolidinesulfonic Acid is a versatile sulfonic acid derivative of pyrrolidone, serving as a key intermediate and reagent in advanced organic synthesis. Its unique structure, featuring both a lactam and a sulfonic acid group, makes it valuable for introducing polar, water-solubilizing motifs into target molecules. This compound is primarily sought by research and development teams in the pharmaceutical and specialty chemical industries for applications ranging from drug discovery to polymer modification.

Application

• Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring sulfonamide or polar functional groups to enhance solubility and bioavailability.
• Polymer Chemistry: Acts as a monomer or modifying agent for creating specialty polymers with enhanced ionic character, water solubility, or specific binding properties.
• Ligand and Catalyst Synthesis: Employed in the preparation of novel ligands for metal catalysis or as a building block for functionalized ionic liquids.
• Bioconjugation Reagent: Useful for modifying peptides, proteins, or other biomolecules by introducing a charged sulfonic acid tag.
• Chemical Research: Serves as a versatile building block in medicinal chemistry and material science research for structure-activity relationship (SAR) studies.
• Surfactant and Detergent Intermediate: Potential use in the synthesis of specialized anionic surfactants due to its sulfonic acid functionality.

Basic Information

Product Name	2-Oxo-1-Pyrrolidinesulfonic Acid
CAS No.	138223-04-8
Molecular Formula	C₄H₇NO₄S
Molecular Weight	165.17 g/mol
Synonyms	1-Pyrrolidinesulfonic acid, 2-oxo-; N-Sulfopyrrolidone; 2-Pyrrolidonesulfonic acid; Pyrrolidine-1-sulfonic acid, 2-oxo-; 1-Sulfopyrrolidin-2-one; 2-Oxo-pyrrolidine-1-sulfonic acid; N-(Sulfo)-2-pyrrolidone; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 2-Oxo-1-Pyrrolidinesulfonic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.