Description

((6-(4-Methylphenoxy)-4-Pyrimidinyl)Thio)Acetic Acid Hydrazide is a specialized pyrimidine derivative with a reactive hydrazide functional group, making it a valuable chemical intermediate. This compound matters for its role in synthesizing more complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel compounds with targeted biological activities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting specific enzymatic pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators due to its pyrimidine-thioether core structure.
• Chemical Synthesis Reagent: Serves as a versatile precursor for creating heterocyclic compounds, amides, and other derivatives via its reactive hydrazide group.
• Bioconjugation & Linker Chemistry: Potential use in creating chemical linkers for antibody-drug conjugates (ADCs) or other bioconjugation applications.
• Material Science Research: Investigated as a monomer or cross-linking agent for specialty polymers with specific thermal or chemical properties.

Basic Information

Product Name	((6-(4-Methylphenoxy)-4-Pyrimidinyl)Thio)Acetic Acid Hydrazide
CAS No.	137927-72-1
Molecular Formula	C13H14N4O2S
Molecular Weight	290.34 g/mol
Synonyms	2-[[6-(4-Methylphenoxy)-4-pyrimidinyl]thio]acetohydrazide; Acetic acid, 2-[[6-(4-methylphenoxy)-4-pyrimidinyl]thio]-, hydrazide; 2-({6-[(4-Methylphenyl)oxy]-4-pyrimidinyl}thio)acetohydrazide; 4-((6-(p-Tolyloxy)pyrimidin-4-yl)thio)acetohydrazide; ((6-(p-Methylphenoxy)-4-pyrimidinyl)thio)acetic acid hydrazide; p-Methylphenoxy-pyrimidinyl-thio-acetic acid hydrazide
EINECS	Contact for details

Quality Control

Our production of ((6-(4-Methylphenoxy)-4-Pyrimidinyl)Thio)Acetic Acid Hydrazide adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analysis, including identity confirmation by spectroscopic methods and purity assessment by HPLC. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the container has been opened. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.