Description

4-(2-Bromoethyl)Phenylboronic Acid is a versatile and valuable organoboron building block used in advanced organic synthesis. Its bifunctional nature, featuring both a boronic acid group and a bromoethyl moiety, makes it a critical intermediate for constructing complex molecular architectures through cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl and heterobiaryl structures found in drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides requiring specific aryl-alkyl linkages.
• Material Science Research: Serves as a monomer or precursor for creating functionalized polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed in the synthesis of novel bidentate ligands for transition metal catalysis.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Library Synthesis for Drug Discovery: A valuable reagent in parallel and combinatorial chemistry to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	4-(2-Bromoethyl)Phenylboronic Acid
CAS No.	137756-90-2
Molecular Formula	C8H10BBrO2
Molecular Weight	228.88 g/mol
Synonyms	4-(2-Bromoethyl)benzeneboronic Acid; [4-(2-Bromoethyl)phenyl]boronic Acid; 2-(4-Boronophenyl)ethyl Bromide; p-(2-Bromoethyl)phenylboronic Acid; 4-(2-Bromoethyl)benzeneboronic Acid Pinacol Ester (common precursor); B-[4-(2-Bromoethyl)phenyl]boronic Acid; (4-(2-Bromoethyl)phenyl)boronic Acid
EINECS	Contact for details

Quality Control

Our 4-(2-Bromoethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.