Description

4-Sulfocalix[8]Arene CAS NO 137407-62-6 is a water-soluble, sulfonated derivative of calix[8]arene, a macrocyclic host molecule. This compound is valued for its exceptional ability to form stable complexes with a wide range of metal ions and organic guest molecules, making it a powerful supramolecular building block. It is primarily utilized by researchers and manufacturers in advanced material science, analytical chemistry, and pharmaceutical development for applications such as selective ion extraction, chemical sensing, and drug delivery systems.

Application

• Ion-Selective Extraction & Separation: Used as a selective extractant for heavy metal ions and lanthanides in environmental remediation and hydrometallurgy.
• Chemical Sensors & Probes: Serves as a recognition element in electrochemical and optical sensor platforms for detecting specific analytes.
• Catalysis & Reaction Modulation: Acts as a supramolecular catalyst or nano-reactor due to its defined cavity, facilitating specific organic transformations.
• Pharmaceutical & Drug Delivery: Investigated for its potential to form inclusion complexes with drug molecules, enhancing solubility, stability, and targeted release.
• Advanced Material Synthesis: Employed as a functional building block for constructing metal-organic frameworks (MOFs), polymers, and surface-modified nanomaterials.
• Analytical Chemistry: Used as a chiral selector or stationary phase modifier in capillary electrophoresis and chromatography for enantiomer separation.

Basic Information

Product Name	4-Sulfocalix[8]Arene
CAS No.	137407-62-6
Molecular Formula	C80H56O32S8
Molecular Weight	~1681.8 g/mol
Synonyms	p-Sulfonatocalix[8]arene; Calix[8]arenesulfonic Acid; Octasulfonated Calix[8]arene; 4-Sulfonatocalix[8]arene; SC8A; 25,26,27,28-Tetrahydroxycalix[8]arene-5,11,17,23,29,35,41,47-octasulfonic Acid; Water-Soluble Calix[8]arene; Host Molecule SC8.
EINECS	Contact for details

Quality Control

Our 4-Sulfocalix[8]Arene is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and elemental analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, store in a cool, dry place at 15-25°C. For long-term stability, consider storage under an inert atmosphere such as nitrogen or argon. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
pH (1% aqueous solution)	2.0 - 4.0
Sulfonation Degree	≥ 7.5 groups per molecule

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.