Description

Tilmicosin Phosphate is a semi-synthetic macrolide antibiotic derived from tylosin, specifically formulated as a phosphate salt to enhance its stability and solubility. This compound is critically important for its potent activity against key respiratory pathogens in livestock, offering a reliable therapeutic option for veterinarians and animal health producers. It is primarily needed by manufacturers in the veterinary pharmaceutical industry for formulating injectable and water-soluble medications to control and treat respiratory diseases in cattle, swine, and poultry.

Application

• Veterinary Pharmaceuticals: Primary active ingredient in injectable solutions for the treatment of bovine and swine respiratory diseases (BRD and SRD).
• Poultry Health: Used in formulations to combat chronic respiratory disease (CRD) and infectious sinusitis in chickens and turkeys.
• Feed Additives: Incorporated into medicated feed or water-soluble powders for herd-level treatment and disease prevention.
• Aquaculture: Investigated for use in controlling bacterial infections in farmed fish species.
• Research & Development: Serves as a reference standard in analytical laboratories for quality control and method development.
• API Manufacturing: Supplied as a high-purity active pharmaceutical ingredient (API) for GMP-compliant drug production.

Basic Information

Product Name	Tilmicosin Phosphate
CAS No.	137330-13-3
Molecular Formula	C46H80N2O13 • H3PO4
Molecular Weight	~ 965.1 g/mol (as phosphate salt)
Synonyms	Tilmicosin Dihydrogen Phosphate; Tilmicosin Phosphate Salt; EL-870; 20-Deoxo-20-(3,5-dimethylpiperidin-1-yl)desmycosin Phosphate; Micotil Phosphate; Pulmotil (brand name basis); (3R,4R,5S,6R,8R,9R,10E,12E,15R)-5-[[3,6-Dideoxy-4-O-(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-3-(dimethylamino)-β-D-glucopyranosyl]oxy]-6-[[2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl]oxy]-9-ethyl-3,4,8,10,12,15-hexamethyl-1-oxacyclopentadeca-10,12-dien-2,13-dione phosphate
EINECS	Contact for details

Quality Control

Our Tilmicosin Phosphate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to ensure it meets high-purity standards suitable for pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with in-house specifications and relevant pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and potency. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC, anhydrous basis)	95.0% - 102.0%
Water (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Heavy Metals	≤ 20 ppm
Microbial Enumeration	Meets standard criteria for non-sterile substances

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.