Description

1,3,2-Dioxaborolane, 4,4,5,5-Tetramethyl-2-[2-(Phenylmethoxy)Ethyl]- is a specialized organoboron reagent featuring a protected pinacol boronate ester group. This compound is a critical building block in modern synthetic chemistry, valued for its stability and reactivity in cross-coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries to construct complex molecular architectures efficiently.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/vinyl halides and boronic esters, essential for synthesizing biaryl structures in drug discovery.
• Pharmaceutical Intermediate Synthesis: Used in the development and scalable production of active pharmaceutical ingredients (APIs) and novel therapeutic candidates.
• Agrochemical Research: Employed in creating novel herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science & OLED Development: Serves as a precursor for constructing organic semiconductors, light-emitting materials, and other functional polymers.
• Chemical Biology & Probe Development: Utilized for bioconjugation and the synthesis of molecular probes for imaging and diagnostic applications.
• Process Chemistry & Scale-Up: Provides a reliable and consistent boron source for transitioning from laboratory-scale research to pilot and commercial manufacturing.

Basic Information

Product Name	1,3,2-Dioxaborolane, 4,4,5,5-Tetramethyl-2-[2-(Phenylmethoxy)Ethyl]-
CAS No.	137297-51-9
Molecular Formula	C15H23BO3
Molecular Weight	262.15 g/mol
Synonyms	2-[2-(Benzyloxy)ethyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; [2-(Benzyloxy)ethyl]boronic acid pinacol ester; (2-(Benzyloxy)ethyl)boronic acid pinacol ester; 2-(2-(Benzyloxy)ethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Benzyloxyethyl pinacol boronate; 2-(Benzyloxymethyl)ethylboronic acid pinacol ester; B-[2-(Phenylmethoxy)ethyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our production of 1,3,2-Dioxaborolane, 4,4,5,5-Tetramethyl-2-[2-(Phenylmethoxy)Ethyl]- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized by advanced analytical techniques including NMR, HPLC, and GC. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.