Description

10-[[3-[[(Phenethylamino)Carbonyl]Amino]-3,6-Dideoxy-α-L-Talopyranosyl]Oxy]-1-Azacyclotetradecan-2-One is a complex, high-purity chemical intermediate of significant interest in advanced pharmaceutical synthesis. Its intricate molecular architecture, featuring a macrolactam core linked to a modified sugar moiety, makes it a valuable precursor for the development of novel therapeutic agents. This compound is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the discovery and production of specialized antibiotics and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel macrolide and glycopeptide antibiotic candidates.
• Medicinal Chemistry Research: Used as a key scaffold for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• API Development: Employed in the research and development stages of new Active Pharmaceutical Ingredients (APIs) targeting bacterial infections.
• Bioconjugation Studies: The reactive functional groups enable its use in creating targeted drug conjugates or probes.
• Process Chemistry: Acts as a benchmark or starting material for scaling up synthetic routes in process optimization.

Basic Information

Product Name	10-[[3-[[(Phenethylamino)Carbonyl]Amino]-3,6-Dideoxy-α-L-Talopyranosyl]Oxy]-1-Azacyclotetradecan-2-One
CAS No.	137120-14-0
Molecular Formula	C30H47N3O7
Molecular Weight	561.72 g/mol
Synonyms	1-Azacyclotetradecan-2-one, 10-[[3-[[(2-phenylethylamino)carbonyl]amino]-3,6-dideoxy-α-L-talopyranosyl]oxy]-; 10-O-[3-[[(2-Phenylethylamino)carbonyl]amino]-3,6-dideoxy-α-L-talopyranosyl]-1-azacyclotetradecan-2-one; Erythromycin derivative intermediate; Macrolactam-sugar conjugate; Talopyranosyl azacyclotetradecanone derivative
EINECS	Contact for details

Quality Control

Our 10-[[3-[[(Phenethylamino)Carbonyl]Amino]-3,6-Dideoxy-α-L-Talopyranosyl]Oxy]-1-Azacyclotetradecan-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.