Description

1-Fluoro-Cyclopropanecarboxylic Acid is a versatile fluorinated cyclopropane derivative, a high-value building block prized for its unique three-membered ring structure and fluorine atom. This combination is critical for modulating the physicochemical properties, metabolic stability, and binding affinity of target molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and advanced material scientists for the synthesis of novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for introducing the metabolically stable cyclopropane motif.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic materials with tailored electronic or surface properties.
• Fluorine Chemistry Building Block: Essential for medicinal chemistry programs focused on fluorine scan (F-scans) and bioisosteric replacement strategies.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Item	Detail
Product Name	1-Fluoro-Cyclopropanecarboxylic Acid
CAS No.	137081-41-5
Molecular Formula	C4H5FO2
Molecular Weight	104.08 g/mol
Synonyms	1-Fluorocyclopropane-1-carboxylic Acid; Fluorocyclopropanecarboxylic Acid; 1-Fluoro-1-carboxycyclopropane; Cyclopropanecarboxylic acid, 1-fluoro-; 1-Fluorocyclopropanecarboxylic acid; 1-Fluorocyclopropane carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Fluoro-Cyclopropanecarboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent quality suitable for research and development applications. Certificates of Analysis (COA) with full traceability are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.