Description

4-Pyrimidinecarboxylic Acid, 1,4,5,6-Tetrahydro-2-(Hydroxymethyl)- (9Ci) is a specialized heterocyclic building block featuring both a carboxylic acid and a hydroxymethyl functional group on a partially saturated pyrimidine core. This unique bifunctional structure makes it a versatile intermediate for synthesizing complex molecules in advanced research and development. It is primarily needed by pharmaceutical and agrochemical R&D teams for creating novel active ingredients and by fine chemical manufacturers producing custom intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating chelating ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic and Institutional Research: A valuable compound for methodological studies in organic chemistry and heterocyclic chemistry.
• Material Science Precursor: Potential use in the synthesis of organic frameworks or functional polymers with specific electronic properties.

Basic Information

Product Name	4-Pyrimidinecarboxylic Acid, 1,4,5,6-Tetrahydro-2-(Hydroxymethyl)- (9Ci)
CAS No.	137023-68-8
Molecular Formula	C7H10N2O3
Molecular Weight	170.17 g/mol
Synonyms	2-(Hydroxymethyl)-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid; 1,4,5,6-Tetrahydro-2-(hydroxymethyl)-4-pyrimidinecarboxylic acid; Tetrahydro-2-(hydroxymethyl)pyrimidine-4-carboxylic acid; 2-Hydroxymethyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid; 4-Carboxy-2-hydroxymethyl-1,4,5,6-tetrahydropyrimidine; THP-4-CA (abbrev.); CAS 137023-68-8
EINECS	Contact for details

Quality Control

Our production of 4-Pyrimidinecarboxylic Acid, 1,4,5,6-Tetrahydro-2-(Hydroxymethyl)- (9Ci) adheres to a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure consistent high quality and batch-to-batch reproducibility. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.