Description

2-(2,2-Dimethylcyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. This compound matters because it provides a protected, air-stable boronic acid equivalent, enabling complex cross-coupling reactions critical for pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex biaryl and heterobiaryl structures for active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Used in the research and development of new drug candidates, particularly in constructing cyclopropyl-containing motifs which are valuable pharmacophores.
• Agrochemical Development: Employed in creating novel herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science & OLED Research: Serves as a precursor for synthesizing organic semiconductors, ligands for catalysts, and novel polymers with specific electronic properties.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and tags for studying biological processes and target engagement.
• Process Chemistry & Scale-Up: Offers a stable and handleable alternative to sensitive boronic acids for optimizing and scaling manufacturing routes.

Basic Information

Product Name	2-(2,2-Dimethylcyclopropyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	136835-34-2
Molecular Formula	C₁₁H₂₁BO₂
Molecular Weight	196.10 g/mol
Synonyms	2-(2,2-Dimethylcyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2,2-Dimethylcyclopropyl)boronic acid pinacol ester; 2,2-Dimethylcyclopropaneboronic acid pinacol ester; Pinacol (2,2-dimethylcyclopropyl)boronate; (2,2-Dimethylcyclopropyl)BPin; 136835-34-2; Cyclopropaneboronic acid, 2,2-dimethyl-, 1,1,2,2-tetramethylethylene ester
EINECS	Contact for details

Quality Control

Every batch of our 2-(2,2-Dimethylcyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is produced and tested under strict quality management systems. We guarantee high chemical purity and lot-to-lot consistency to ensure reliable performance in your sensitive synthetic applications. Comprehensive analytical testing, including NMR (¹H, ¹³C, ¹¹B), GC/HPLC, and Karl Fischer titration, is performed. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C (refrigerated) for long-term stability, as the compound is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to prevent moisture condensation. Keep under an inert atmosphere (argon or nitrogen) for optimal shelf life.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.