Description

8-Bromo-2-Chloro-7-Methoxyquinoline-3-Carboxaldehyde is a high-purity, multi-functional quinoline derivative that serves as a critical advanced intermediate in modern organic synthesis. Its unique halogenated and formylated structure makes it an indispensable building block for constructing complex heterocyclic systems with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting neurological disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its quinoline core for bioactivity.
• Material Science: Serves as a building block for creating organic ligands, dyes, and photoactive compounds used in electronic materials and sensors.
• Chemical Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a formyl donor for constructing fused heterocycles and complex molecular architectures.
• Academic & R&D: Essential for methodological studies in organic chemistry and for exploring new reaction pathways in medicinal chemistry.

Basic Information

Product Name	8-Bromo-2-Chloro-7-Methoxyquinoline-3-Carboxaldehyde
CAS No.	136812-28-7
Molecular Formula	C11H7BrClNO2
Molecular Weight	300.54 g/mol
Synonyms	8-Bromo-2-chloro-7-methoxy-3-quinolinecarboxaldehyde; 3-Formyl-8-bromo-2-chloro-7-methoxyquinoline; 2-Chloro-8-bromo-7-methoxyquinoline-3-carbaldehyde; 136812-28-7; Quinoline-3-carboxaldehyde, 8-bromo-2-chloro-7-methoxy-; 8-Bromo-2-chloro-7-methoxy-quinoline-3-carboxaldehyde
EINECS	Contact for details

Quality Control

Every batch of 8-Bromo-2-Chloro-7-Methoxyquinoline-3-Carboxaldehyde is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.