Description

Pyridine-2-Boronic Acid Dimethyl Ester is a versatile and highly valuable organoboron reagent, specifically a protected boronic acid derivative. This compound is essential as a key synthetic intermediate in modern cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for building novel pyridine-containing scaffolds.

Application

• Pharmaceutical Intermediate: A crucial building block in Suzuki-Miyaura cross-couplings for synthesizing active pharmaceutical ingredients (APIs) and drug candidates containing bipyridine or arylpyridine motifs.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and insecticides that require specific pyridine-based structures for enhanced activity.
• Material Science & OLED Development: Serves as a precursor for creating organic light-emitting diode (OLED) materials, electron-transport layers, and coordination complexes for catalysis.
• Ligand Synthesis for Catalysis: Employed in the preparation of sophisticated pyridine-based ligands used in homogeneous catalysis for fine chemical manufacturing.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and bioconjugates for studying biological systems and diagnostic applications.
• Academic & Contract Research: A fundamental reagent for methodological development in organic synthesis and for producing custom compounds in contract research organizations (CROs).

Basic Information

Product Name	Pyridine-2-Boronic Acid Dimethyl Ester
CAS No.	136805-54-4
Molecular Formula	C8H12BNO2
Molecular Weight	165.00 g/mol
Synonyms	2-(Dimethoxyboryl)pyridine; Pyridine-2-boronic acid dimethyl ester; 2-Pyridinyldimethoxyborane; Dimethyl pyridine-2-ylboronate; 2-Pyridylboronic Acid Dimethyl Ester; 2-(Dimethyloxyboranyl)pyridine; 2-Pyridylboronate Dimethyl Ester; B-(2-Pyridyl)boronic Acid Dimethyl Ester
EINECS	Contact for details

Quality Control

Our Pyridine-2-Boronic Acid Dimethyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency. Certificates of Analysis (COA) with full specification data are available upon request for quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term stability and to prevent hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.