Description

D-Altro-Nonitol, 1,2,3,6-Tetradeoxy-3-Methyl-5-o-Methyl-8,9-o-(1-Methylethylidene)-7-o-(Phenylmethyl)-, (3.Xi.)- is a complex, high-purity carbohydrate derivative with a defined stereochemistry and protective groups, making it a valuable chiral building block for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals, particularly in the synthesis of nucleoside analogs, antiviral agents, and complex natural products. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on innovative drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of potential antiviral and anticancer drug candidates.
• Nucleoside Analog Research: Used in the development of modified nucleosides for probing biological mechanisms or creating new therapeutic agents.
• Glycochemistry & Glycobiology: Acts as a protected sugar derivative for constructing complex oligosaccharides or glycomimetics.
• Asymmetric Synthesis: Provides a source of chirality for the synthesis of other enantiomerically pure compounds in medicinal chemistry.
• Process Chemistry Development: Employed in scaling up synthetic routes for active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes to study carbohydrate-protein interactions.

Basic Information

Product Name	D-Altro-Nonitol, 1,2,3,6-Tetradeoxy-3-Methyl-5-o-Methyl-8,9-o-(1-Methylethylidene)-7-o-(Phenylmethyl)-, (3.Xi.)-
CAS No.	136759-81-4
Molecular Formula	C22H34O5
Molecular Weight	378.51 g/mol
Synonyms	1,2,3,6-Tetradeoxy-3-methyl-5-O-methyl-8,9-O-(1-methylethylidene)-7-O-(phenylmethyl)-D-altro-nonitol; D-altro-Nonitol, 1,2,3,6-tetradeoxy-3-methyl-5-O-methyl-8,9-O-(1-methylethylidene)-7-O-(phenylmethyl)-, (3ξ)-; Benzyl 3-C-methyl-2,3,6-trideoxy-4,5-O-isopropylidene-β-D-ribo-hexofuranoside; Protected D-altro-Nonitol derivative; Chiral carbohydrate building block; Benzyl-protected sugar alcohol derivative.
EINECS	Contact for details

Quality Control

Our D-Altro-Nonitol derivative is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and optical rotation measurement to verify chiral integrity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Optical Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.