Description

1,7-Dioxaspiro5.5Undecane-4,5-Diol, (4.Alpha.,5.Alpha.,6.Beta.)- CAS NO 136758-36-6 is a high-purity, stereochemically defined spirocyclic diol compound. This specialized intermediate is valued for its unique rigid molecular framework and dual hydroxyl functionality, which are critical for constructing complex molecules in advanced synthesis. It is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis, chiral catalyst development, and the production of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized as a precursor or auxiliary in stereoselective reactions to create enantiomerically pure compounds.
• Ligand and Catalyst Development: Serves as a core structure for designing novel chiral ligands and organocatalysts.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.
• Academic and Industrial R&D: Used in chemical research to explore new synthetic methodologies and molecular architectures.
• Material Science: Potential monomer or cross-linking agent for developing specialized polymers with unique properties.

Basic Information

Item	Details
Product Name	1,7-Dioxaspiro5.5Undecane-4,5-Diol, (4.Alpha.,5.Alpha.,6.Beta.)-
CAS No.	136758-36-6
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	(4α,5α,6β)-1,7-Dioxaspiro[5.5]undecane-4,5-diol; 4α,5α,6β-1,7-Dioxaspiro[5.5]undecane-4,5-diol; (4R,5R,6S)-1,7-Dioxaspiro[5.5]undecane-4,5-diol; Spirocyclic diol; 1,7-Dioxaspiro[5.5]undecane-4,5-diol stereoisomer; CAS 136758-36-6
EINECS	Contact for details

Quality Control

Every batch of our 1,7-Dioxaspiro5.5Undecane-4,5-Diol is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure high chemical and stereochemical purity, meeting the stringent requirements of research and cGMP-grade production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture uptake and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.